Mishnah Berurah — משנה ברורה

To pray and remove - Meaning, regarding [washing for] praying there is an uncertainty if the reason for washing hands in the morning is like the Rashb"a [mentioned] above in Mishnah Berurah se'if katan 1, therefore, even though he is not considered a new creation right now [since he was up all night], [nevertheless] the sages did not make a distinction (ie. they established that one must wash in the morning, regardless of whether they slept or not) and he would need to wash. Or maybe the main reason is like the Ro"sh [mentioned] there, and since he was up all night and he didn't touch any unclean parts [of his body], there is no need to wash. And [regarding] removing the evil spirit, there is also an uncertainty if, in general, sleep causes the evil spirit [to come onto one's hands], and therefore, even if one slept during the day, the evil spirit rests there and one must wash their hands, and [accordingly], one who stayed up all night does not need to wash their hands. Or [maybe] it's the nighttime which causes the evil spirit [to come], and therefore the law would be the opposite [of what was mentioned here].